颅内毛细胞型星形细胞瘤的诊治及预后.pdfVIP

160 J Clin Neurosurg，December 2007，Vo1．4，No．4 · 论著 · 颅内毛细胞型星形细胞瘤的诊治及预后 金浩，王汉东 【摘要】 目的 探讨颅内毛细胞型星形细胞瘤的病理学特点、临床特点、影像学表现和治疗经验。方法 回顾性分析南京军区总医院神经外科2002年6月至2006年6月四年间20例经手术病理证实的毛细胞型星 形细胞瘤临床资料。分析其影像学特点及术中所见和预后情况。结果 20例肿瘤均接受显微外科手术，根 据肿瘤所在部位采取不同手术入路。16例全切，4例大部分切除，4例均位于视交叉或下丘脑部，与周边重要 神经结构粘连较紧。结论 顷内毛细胞型星形细胞瘤为良性肿瘤，显微手术全切预后良好，对于未全切病例 术后行恰当的放疗或化疗也能获得理想效果。 【关键词】 毛细胞型星形细胞瘤，影像学表现，显微外科手术，预后 【中图分类号】R730．264 【文献标识码】A 【文章编号】1672·7770(2007)04-0160-02 Treatment and prognosis of pilocytic astrocytoma jlN Hao．WANG Han—dong．Department ofNeurosurgery， Wujiang Hospital Affiliated to Nantong University，Wujiang 215000，China Abstract：0bjective To investigate the pathology and clinical characteristics，radiological appearence and the therapeutic experience of pilocytic astrocytoma．Methods Retrospective analysis of 20 patients with pilocytic astrocytoma proved by pathology in our clinic was conducted．The features of images，surgmy and prognosis were analyzed．Results Microsurgical resection was performed in all 20 CaSeS．Different surgical approaches were used according to the tumor site．Total removal of the tumor in 1 6 of 20 cases，and subtotal removed in 4 of 20 cases．4 tumors were f0und in the mtrochiasm or hyp0thalamus．and adhesive strictly to the important surrounding structures． Conclusions The pilocytic astrocytoma is a benign intracranial trmor with good prognosis after microsurgical resection．Combined with chemotherapy and／or radiotherapy after operation is effective in partial resection． Key words：pilocytic astrocytoma； radiological appearence；microsurgery； prognosis 毛细胞型星形细胞瘤发病率较低，约占中枢神 泌乳1例；癫痫伴肢体乏力1例；视物模糊3例。眼 经系统肿瘤1．5％ 。多见于：．bJL及年轻人，好发 底检查见视盘静脉扩张和视乳头水肿6例，有脑积 于小脑、第三脑室和视神经等中线部位。回顾性分 水者5例。 析本人在南京军区总医院神经外科进修期问该科自