从血浊内阻论治短暂性脑缺血发作的临床探究.pdfVIP

提 要 目的：以“血浊理论”为依据，观察化浊行血汤治疗短暂性脑缺血发作的临床疗 效，并探讨其作用机制。方法：60 例短暂性脑缺血发作病人随机分为 A 、B 两组， 每组 30 例。A 组为治疗组，在西医常规治疗基础上加服化浊行血汤；B 组为对照组， 予以西医常规治疗基础。治疗周期为 3 个月。观察治疗前后患者主要临床症状，治疗 期间每个疗程 TIA 发作次数，血脂，血液流变学，血清细胞间黏附分子（ICAM-1 ）、 P-选择素（P-selectin ）等水平的变化。结果：治疗组治疗后临床症状的有效率及临床 总疗效与对照组相比，有显著性差异。治疗组能明显降低 TIA 患者的发作次数，缩 短发作时间，与对照组相比，有显著性差异。治疗组治疗后 TC、TG、LDL-C 水平明 显下降，全血高切粘度、低切粘度、血浆黏度、纤维蛋白原水平明显下降，血清ICAM-1、 P-selectin 水平明显下降，与对照组相比，均有显著性差异。结论：化浊行血汤能明 显改善 TIA 患者的临床症状，提高临床疗效，显著改善血脂代谢紊乱，降低血液高 凝状态，保护血管内皮，延缓动脉粥样硬化的发展过程，有效预防了脑卒中的发生。 其研究结果为短暂性脑缺血发作的防治提供了新的思路和方法。 关键词 血浊；化浊行血汤；短暂性脑缺血发作；临床研究 The clinical research of discussing from the blood muddy interface resistance governs transient ischemic attack SPeciality: Experimental and clinical study on the treatment of nervous system diseases with Traditional Chinese Medicine Tutor: Prof Wang Xinlu Author: Liu Qingming Abstract Objective:Take “the blood muddy theory” as the basis, the observation muddy good blood souP treatment transient is chemic attack the clinical curative effect, and discusses its function mechanism.Methods: 60 examPles transient ischemic attack Patients are divided into A and B grouPs stochastically, each grouP of 30 examPles.A grouP is the treatment grouP, adds the clothing muddy good blood souP in the doctor Practicing western medicine convention treatment foundation; B grouP is a control grouP, adds the clothing length of stride brain heart in the doctor Practicing western medicine convention treatment foundation to Pass.The treatment cycle is 3 months. Around the observation treatment the Patient main clinical symPtom, the treatment Period each treatment course TIA outbreak number of times, the blood fats, the blood rheology, the blo