健脾利湿清窦方治疗急性鼻窦炎脾胃湿热证的临床探究.pdfVIP

提 要 目的：观察健脾利湿清窦方治疗急性鼻窦炎或慢性鼻窦炎急性发作期，中医辨证 为脾胃湿热型的临床疗效，并从理论和临床研究两个方面探讨健脾利湿清窦方治疗脾 胃湿热型鼻窦炎的机制。 方法：于确诊为急性鼻窦炎或慢性鼻窦炎急性发作期患者中，筛选出符合本研究 之纳入条件的患者60例，并将其随机分为健脾利湿清窦方组和藿胆丸组。治疗组（30） 例，给予健脾利湿清窦方，对照组（30）例，给予藿胆丸，观察 10 天。症状评估采 用主症、次症及体征计分，计有鼻塞、鼻腔分泌物、鼻粘膜充血及鼻甲肿大、头昏头 痛、嗅觉减退5种评估项目，最后将两组的结果加以分析比较，观察两组的临床疗效。 结果：临床研究显示，治疗组中医证候疗效优于对照组（P0.05或P0.01）。治 疗组能明显改善鼻塞、鼻涕黄浊量多、头昏头痛等症状，其疗效优于对照组（P0.05 或P0.01）。两组治疗期间均未发生不良反应。 结论：健脾利湿清窦方是治疗脾胃湿热型急性鼻窦炎或慢性鼻窦炎急性发作期的 有效方剂，其机理可能与调节机体免疫、抗菌抗病毒抗炎、改善微循环等有关。 关键词 健脾利湿清窦方；急性鼻窦炎（Acute Sinusitis）； 脾胃湿热 ；临床 研究 A Clinical Study of Treating Spleen and Stomach Damp-heat Syndrome of Acute Sinusitis with Jianpilishiqingdoufang Specialty：Otorhinolaryngology of TCM. Author ：Xue Lian Tutor：Professor Gu Zhen Abstract Objective:To observe the effect of Jianpilishiqingdoufang （JPLSQDF ）on Spleen and Stomach Damp-heat Syndrome of Acute Sinusitis and acute exacerbation of chronic sinusitis and explore the mechanism of it. Methods: 60 patients with Treating Spleen and Stomach Damp-heat Syndrome Sinusitis were divided into two groups at random:the treatment group and the control group. The treatment group was given JPLSQDF, and the control group was given Huodanwan (HDW).10 days were set as a course of treatment. Symptom assessment were completed through at the main symptom, sub-symptom and physiological signs of the patients, such as stuffy nose, nasal secretions,hyperemia and swelling of nasal mucosa,dizziness nausea or pain, dysosmia.The clinical effects of each group were observed during the course . Results: The effect on syndrome of TCM are better than that of the control group (P ＜0.01 or P ＜0.05). JPLSQDF indicates significantly better than H