加味救母丹治疗药物流产后异常出血（气虚血瘀证）的临床探究.pdfVIP

提 要 目的：观察加味救母丹治疗药物流产后异常出血 （气虚血瘀证）在临床上的疗效， 并初步探讨其作用机理，为其应用于临床提供科学依据。方法：将60例药物流产后异 常出血患者随机分为两组，治疗组30例，口服加味救母丹水煎剂治疗，对照组30例， 口服参坤养血颗粒治疗，连续用药7天。观察两组患者治疗前后临床症状、体征的改 善情况，比较两组治疗前后的止血疗效及子宫三径和宫腔内回声、红细胞总数、血红 蛋白、血小板总数、血浆凝血酶原时间、血ß-HCG、血浆一氧化氮（NO）的变化。结 果：在止血疗效上，两组总有效率分别为93.3%、80.0%，两组比较有极显著性差异（P ＜0.01）。中医证候疗效上，治疗组与对照组临床总有效率分别为96.7%、83.3%，两 组比较有显著性差异（P＜0.05）；治疗组在改善患者子宫三径及宫腔内回声，降低 血ß-HCG、血浆一氧化氮（NO）方面明显优于对照组（P＜0.01或P＜0.05）。结论： 加味救母丹对于药物流产后异常出血（气虚血瘀证）具有良好的止血效果，可明显改 善患者的伴随症状。其作用机理可能与促进子宫收缩、降低血ß-HCG、血一氧化氮 （NO） 有关。 关键词 药物流产后异常出血；气虚血瘀；加味救母丹；临床研究 Clinical research on the Treatment of bleeding after Drug bortion( Qi deficiency and blood stasis) with flavored saves mother Dan Speciality：Gynecology of Traditional Chinese Medicine Author ：YuJie Tutor：Professor WangZhe Abstract Objective ：To observe the clinical efficacy of flavored saves mother Dan on treating bleeding after Drug bortion( Qi deficiency and blood stasis) , and to explore its mechanism of action ，and provide scientific basis for its clinical application. Methods ：60 cases of bleeding after Drug bortion were randomly divided into two groups,30 cases of treatment group treated with flavored saves mother Dan,and 30 cases of the control group treated with Shenkunyangxue particles. Both groups continuous treatment for 7 days. Before and after treatment,the improvement of two groups patients in clinical symptoms and signs, the hemostatic effect and the development of the uterine three diameters and uterine cavity echo ，total number of red blood cells and platelet, hemoglobin,plasma prothrombin time(PT) ，ß-biood human chorionic gonadotropin (ß-HCG ) and nitric o