参芪固冲饮治疗气虚血瘀型围绝经期无排卵性功血出血期的临床探究.pdfVIP

提 要 目的：观察参芪固冲饮治疗气虚血瘀型围绝经期无排卵性功血出血期的疗效并探 讨其止血机理。方法：选择60例气虚血瘀型围绝经期无排卵性功血出血期患者，治疗 组30例（口服参芪固冲饮），对照组30例（口服宫血停颗粒），观察两组患者止血疗 效、血栓烷B （TXB）、6-酮-前列腺素（6-K-PGF ），T淋巴细胞亚群（CD3、CD4、 2 2 1а CD4/CD8）、子宫内膜血管内皮生长因子（VEGF）含量的变化。结果：两组止血效果 显著，症状改善明显，治疗组差异有显著性（P＜0.01或P＜0.05），组间比较差异有 显著性（P＜0.05）；疗后两组血6-K-PGF 、6-K-PGF /TXB 降低、子宫内膜VEGF含 1а 1а 2 量提高、T淋巴细胞亚群指标改善明显，治疗组差异有显著性（P＜0.01或P＜0.05）， 组间比较差异有显著性（P＜0.05）。结论：参芪固冲饮对气虚血瘀型围绝经期无排 卵性功血出血期止血效果明显。其机理可能与改善微循环、增强机体免疫功能、抗菌 消炎、促进子宫内膜微血管修复等有关。 关键词 参芪固冲饮；气虚血瘀型；围绝经期无排卵性功血；临床研究 The Clinical Study of Shenqi Guchong Yin in Treating Perimenopausal Dysfunctional Uterine Bleeding with Blood Stasis and Qi Deficiency Form Specialty: Gynecology of Traditional Chinese Medicine Author: SongWei Tutor: Prof. YeQing Abstract Objective: To investigate the hemostasis effect of Shenqi Guchong Yin in treating perimenopausal dysfunctional uterine bleeding with blood stasis and qi deficiency form and its mechanism. Methods: 60 cases of perimenopausal dysfunctional uterine bleeding with blood stasis and qi deficiency form, were divided randomly into treatment group (30 cases, treated with SGY) and control group (30 case, treated with GXTG). To observed cases with hemostasis effect, clinical symptoms, Thromboxane B2 (TXB2), 6-keto-prostaglandin F1а (6-K-PGF1а), the T-lymphocyte subsets (CD3 and CD4, CD4/CD8), endometrial vascular endothelial growth factor (VEGF) in change. Results: The hemostasis effect of two g