降糖通络合剂治疗2型糖尿病合并类风湿关节炎的临床探究.pdfVIP

提 要 目的: 观察降糖通络合剂治疗 2 型糖尿病合并类风湿关节炎的临床疗效。方法: 在基础降糖的前提下，将临床诊断为 2 型糖尿病合并类风湿关节炎的 60 例患者随机 分为两组，其中治疗组 30 例，给予降糖通络合剂治疗；对照组 30 例，给予白芍总苷 胶囊（帕夫林）治疗，两组均以 4 周为一个疗程，连用 2 个疗程。结果: 经临床观察， 治疗组在改善本病的症状和体征方面优于对照组（P0.05 ）；在降低空腹（FBG ）及 餐后 2 小时血糖（PBG ）、糖化血红蛋白（HbA c ）方面明显优于对照组（P0.05 ）； 1 在改善免疫及炎性指标血沉（ESR ）、C 反应蛋白（CRP ）、类风湿因子（RF ）方面优 于对照组（P0.05 ）；并且在治疗过程中未发生不良反应。结论: 临床观察表明降糖 通络合剂治疗 2 型糖尿病合并类风湿关节炎的疗效可靠，无明显不良反应，值得进一 步研究。 关键词 2型糖尿病；类风湿关节炎；降糖通络合剂；临床研究 Clinical Study on Treatment of Type 2 Diabetes Mellitus Coexisted with Rheumatoid Arthritis with Jiangtangtongluo Mixture Speciality: Internal Medicine of TCM Author: Shen Guangli Tutor: Professor Guo Baorong Abstract Objective:To observe the therapeutic effect of Jiangtangtongluo mixture in treating type 2 Diabetes Mellitus coexisted with Rheumatoid Arthritis. Methods:60 patients diagnosed type 2 Diabetes Mellitus coexisted with Rheumatoid Arthritis were randomly classified into two groups.Under the basic premise of reducing the blood plasma glucose, 30 patients were treated with Jiangtangtongluo mixture in treated group,others were treated with capsules of TGP (Mofulin) in control group.All of the groups were treated four 4 weeks as a course,taken for 2 courses. Results: Jiangtangtongluo mixture could improve the singns and symptoms obviously.The difference was singnificant compared to the control group （P0.05 ）.And it also could decrease fasting blood glucose (FBG) ,2 hours postprandial blood glucose (PBG) and glycosylated hemoglobin (HbA c) obviously 1 superior to the c