中西医结合治疗肝硬化腹水50例临床观察.docVIP

中西医结合治疗肝硬化腹水50例临床观察【摘要】目的:对中西医结合治疗的肝硬化腹水的疗效进行临床观察。方法:将64例肝硬化腹水患者随机分为观察组（采用中西医结合治疗）和对照组（采用常规护肝治疗），对两组的临床疗效和治疗前后的肝功能情况进行比较。结果:与对照组相比，治疗组显效和总有效的比例明显增加，无效的比例明显降低，差异具有统计学意义（p＜0.05）；与此同时，治疗组治疗后与治疗前及对照组治疗后相比，总蛋白和白蛋白显著升高，谷丙转氨酶（ALT）显著降低，差异具有统计学意义（p＜0.05）。讨论中西医结合治疗肝硬化腹水，能有效改善肝功能，调节机体免疫，降低门脉高压，使血脉通畅，纤维降解，腹水消退，因而是治疗肝硬化腹水行之有效的方法。 【关键词】中西医结合；肝硬化腹水 Integrative Medicine Clinical observation of 50 cases of liver cirrhosis Zhang BaiJian 【Abstract】ObjectiveTO Integrative Medicine of the clinical efficacy of liver cirrhosis observed. Methods 50 patients with liver cirrhosis were randomly divided into two groups (TCM-WM therapy) and control group (conventional liver protection therapy), clinical efficacy and the two groups of liver function before and after treatment were compared. Results Compared with the control group, treatment group and significantly increased the proportion of the total effective, significantly reduced the proportion of invalid, the difference was statistically significant (p 0.05); At the same time, the treatment group before and after treatment in the control group After the comparison, total protein and albumin were significantly increased, alanine aminotransferase (ALT) significantly decreased, the difference was statistically significant (p 0.05). Conclusions The discussion of Integrative Medicine ascites due to cirrhosis, can improve liver function, immune regulation, reducing portal hypertension, the blood vessels smooth, fiber degradation, ascites subsided, so it is an effective method of treatment of ascites due to cirrhosis. 【Key words】 ascites due to cirrhosis of Integrative Medicine 【中图分类号】R854【文献标识码】B【文章编号】1005-0515(2011)03-0317-02 肝硬化是一种慢性进行发展的疾病，是肝脏纤维化的最后阶段，它以门静脉高压和肝功能不全诱发的一系列并发症为特征，包括腹水、食管胃底静脉曲张破裂出血、肝性脑病、自发性腹膜炎、肝肾综合征和肝癌。肝硬化腹水的出现是肝病发展到晚期的一个重要标志[1]。肝硬化一旦出现腹水，就存在着治疗困难，预后差的特点[2]。 肝硬化腹水是由多种原因长期作用于肝脏引起的肝脏慢性、进行性、弥温性损害。肝细胞广泛坏死，残存肝细胞形成再生结节，结缔组织增生及纤维化，导致正常肝脏结构破坏，假小叶形成，在此基础上显现以肝功能损害和门脉高压为主及腹水形成的临床表现，为临床上难治疾病之一，严重危害患者的生活质量和生命安全[3]。因此，20