胸腔镜术治疗早期非小细胞肺癌疗效评价.docVIP

胸腔镜术治疗早期非小细胞肺癌疗效评价[摘要] 目的 探讨全胸腔镜手术治疗早期非小细胞肺癌的长期疗效。 方法 选取我院临床诊断的早期非小细胞癌患者72例，随机分为全胸腔镜手术组和传统开胸组，术后随访2年，比较两种术式术后1、2年的患者生活质量、生存率情况。 结果 两种术式术后1、2年的生活质量各领域评分的横向比较，差异无统计学意义（P 0.05）。两种术式术后1年的生存率均为100%，术后2年的生存率分别为97.22%、94.44%，差异无统计学意义（P 0.05）。 结论 两组术式术后的生活质量、生存率相当。 [关键词] 早期非小细胞肺癌；全胸腔镜手术；生活质量 [中图分类号] R734.2 [文献标识码] A [文章编号] 1673-7210（2012）07（b）-0044-03 Effect evaluation of video-assisted thoracoscopic surgery in the treatment of early non-small cell lung cancer ZHAO Jing PEI Yingxin LIU Jifu Department of Thoracic Surgery, General Hospital of Beijing Military Region, Beijing 100700, China [Abstract] Objective To evaluate the long-term treatment effect of video-assisted thoracoscopic surgery in the treatment of early non-small cell lung cancer (NSCLC). Methods 72 cases of patients diagnosed with early non-small cell lung cancer were randomly divided into the video-assisted thoracoscopic surgery group and the traditional thoracotomy group. All patients were followed-up for two years after surgery. The quality of life and survival rate were compared after one and two years of operation between the two operation methods. Results The differences in all areas of life quality scores had no statistical significance by horizontal comparison between the two group (P 0.05). The survival rate were 100% in the two groups after one year of surgery, after two year of surgery the survival rate were 97.22% and 94.44% respectively in the two groups, the difference was not statistically significant (P 0.05). Conclusion The quality of life and survival rate were equivalent between the two groups. [Key words] Early non-small cell lung cancer; Video-assisted thoracoscopic surgery; Quality of life 全胸腔镜手术（VATS）创伤小、出血少、术后疼痛轻、恢复快等特点已得到公认，目前已广泛应用于临床早期肺癌的诊断和根治切除。研究表明，VATS治疗非小细胞肺癌（NSCLC）的短期效果较好[1-3]。但有关VATS长期疗效的文献报道很少，特别是术后生活质量的长期前瞻性评价，以至于临床医生对于VATS手术的长期疗效存在疑虑。为此，我院选取了2009年1月～2011年11月的临床早期非小细胞肺癌（NSCLC）患者，分别实施了VATS和传统开胸肺癌根治术，并对两种手术患者术前与术后的生活质量进行了比较，现将研究结果报道如下： 1 资料与方法 1.1 病例纳入及排除标