注射用乳糖酸阿奇霉素治疗小儿支气管肺炎效果观察.docVIP

注射用乳糖酸阿奇霉素治疗小儿支气管肺炎效果观察【摘要】 目的 探讨注射用乳糖酸阿奇霉素治疗小儿支气管肺炎的临床疗效及安全性。 方法 回顾性分析2008年2月至2010年5月期间，在我院收治的80例小儿支气管肺炎患儿，随机分为治疗组与对照组，每组各40例。治疗组给予注射用乳糖酸阿奇霉素，对照组给予注射用阿莫西林克拉维酸钾，密切观察两组患者的临床疗效。 结果 乳糖酸阿奇霉素治疗小儿支气管肺炎的总有效率高于对照组的总有效率，且乳糖酸阿奇霉素组的不良反应发生率明显低于对照组。 结论 乳糖酸阿奇霉素是治疗小儿支气管肺炎临床疗效确切有效、安全性高的抗生素的方法。 【关键词】 乳糖酸；阿奇霉素；小儿；支气管肺炎  Clinical analysis of lactose azithromycin in treatment of children bronchial pneumonia ZHOU Tao.Department of Emergency, Jiangsu Haimen Peoples Hospital,Haimen 226100,China  【Abstract】 Objective To study the clinical analysis of lactose azithromycin in treatment of children bronchial pneumonia. Methods During the period April 2008 to March 2010, the clinical data of 80 cases of children bronchial pneumonia were retrospectively analyzed. They Were randomly divided into treatment group and control group,(n=40).The treatment group received a lactose azithromycin injection, the control group was given Amoxicillin carat d acid potassium. Close observation of the clinical efficacy of the two groups of children. Results Lactose azithromycin treatment in children with bronchial pneumonia efficiency higher than that in the control group the total efficiency, and the incidence of adverse reactions for lactose azithromycin group was significantly lower than the control group. Conclusion Lactose azithromycin was effective treatment of children with bronchial pneumonia, and safe, it was worth to promote the use of clinical. 【Key words】 Lactose acid; Azithromycin; Children;Bronchial pneumonia  小儿支气管肺炎(children bronchial pneumonia)是儿科最多发、常见的一种呼吸道疾病，在一年四季该病均可发生，主要的发病对象是0～16岁的青少年以及儿童，其中，以0～3岁的婴幼儿最为多见，且春季和冬季是小儿支气管肺炎多发的季节［1-2］。由于婴幼儿身体各方面器官发育不完全，免疫力较弱，因此，要及时、有效地进行治疗，减少并发症的发生，保证婴幼儿的正常发育和生长。大量临床研究表明［3-5］，阿奇霉素(Azithromycin)作为15元环大环内酯类抗生素，具有抗菌谱广、半衰期长、与血浆蛋白结合率低、组织渗透性好、感染部位组织及细胞内浓度高等优点，特别是在组织浓度高、剂量低、疗程短、给药结束后其抗菌作用仍能维持6 d之久，是治疗小儿支气管肺炎患儿有效的药物之一。为了明确乳糖酸阿奇霉素治疗小儿支气管肺炎患儿的临床疗效及安全性，及时有效地治患儿，减少患儿的痛苦，使患儿尽快康复出院,对我院在2008年2月至2010年5月期间收治的80例小儿支气管肺炎患儿，结合医院实际静脉给予乳糖酸阿奇霉素治