原创力文档effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (zdf rat)影响sitagliptin治疗dysmetabolism、炎症和氧化应激在2型糖尿病的动物模型(zdf老鼠).pdfVIP
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effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (zdf rat)影响sitagliptin治疗dysmetabolism、炎症和氧化应激在2型糖尿病的动物模型(zdf老鼠)
Hindawi Publishing Corporation
Mediators of Inflammation
Volume 2010, Article ID 592760, 11 pages
doi:10.1155/2010/592760
Research Article
Effects of Sitagliptin Treatment on Dysmetabolism,
Inflammation, and Oxidative Stress in an Animal Model of
Type 2 Diabetes (ZDF Rat)
Liliana Ferreira,1 Edite Teixeira-de-Lemos,1, 2 Filipa Pinto,1 Belmiro Parada,1
2 2 3 ´ 1 ´ 1 1
Cristina Mega, Helena Vala, Rui Pinto, Patrıcia Garrido, Jose Sereno, Rosa Fernandes,
Paulo Santos,4 Isabel Velada,4 Andreia Melo,1 Sara Nunes,1 Frederico Teixeira,1, 5
´ 1, 5
and Flavio Reis
1 Institute of Pharmacology Experimental Therapeutics, IBILI, Medicine Faculty, University of Coimbra, 3000-354 Coimbra, Portugal
2 ESAV, Polytechnic Institute of Viseu, 3500 Viseu, Portugal
3 Pharmacology Pharmacotoxicology Unit, Faculty of Pharmacy, Lisbon University, 1649-003 Lisboa, Portugal
4 Functional Genomics Laboratory, Center of Histocompatibility of the Centre, 3001-301 Coimbra, Portugal
5 Institute for Molecular and Cellular Biology, Porto University, 4150 Porto, Portugal
´
Correspondence should be addressed to Flavio Reis, freis@fmed.uc.pt
Received 28 January 2010; Revised 17 April 2010; Accepted 28 April 2010
¨
Academic Editor: Gema Fruhbeck
Copyright © 2010 Liliana Ferreira et al. This is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The purpose of
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