does ph of tyrode solution modify glucose and electrolyte jejunal absorption in ratsph值的tyrode解决方案修改葡萄糖和电解质在大鼠空肠的吸收.pdfVIP

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does ph of tyrode solution modify glucose and electrolyte jejunal absorption in ratsph值的tyrode解决方案修改葡萄糖和电解质在大鼠空肠的吸收.pdf

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does ph of tyrode solution modify glucose and electrolyte jejunal absorption in ratsph值的tyrode解决方案修改葡萄糖和电解质在大鼠空肠的吸收

Vol.3, No.2, 127-131 (2012) Journal of Biophysical Chemistry /10.4236/jbpc.2012.32014 Does pH of tyrode solution modify glucose and electrolyte jejunal absorption in rats? * Elizabeth Lage Borges , Marcelo de Pinho Viana Departamento de Fisiologia e Biofísica, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; * Corresponding Author: borgesel@icb.ufmg.br Received 14 December 2011; revised 29 January 2012; accepted 10 February 2012 ABSTRACT dification is not caused by glucose transport alone [3]. This effect is reproduced when the substrate is adminis- Studies have shown that glucose is able to de- tered in vivo [1]. It is plausible that the generation of crease the pH of the surface epithelium jejunal protons, which are secreted into this region, is closely re- preparations when added in vitro and the exis- lated to the intracellular metabolism of glucose and lac- tence of a high concentration of protons in the tate production. The existence of a high concentration of immediate area of the mucosa could be of con- protons in the immediate surface of the mucosa could be siderable significance for absorption of electro- of considerable significance for the absorption of elec- lytes. The aim of this study is to assess whether