dynamic tracking of lung deformation during breathing by using particle method肺的动态跟踪变形期间呼吸用粒子的方法.pdfVIP

Hindawi Publishing Corporation Modelling and Simulation in Engineering Volume 2009, Article ID 190307, 7 pages doi:10.1155/2009/190307 Research Article Dynamic Tracking of Lung Deformation during Breathing by Using Particle Method Subas Chhatkuli,1 Seiichi Koshizuka,2 and Mitsuru Uesaka3 1 Department of Nuclear Engineering and Management, The University of Tokyo, 2-11-6 Yayoi, Bunkyo-Ku, Tokyo 113-0032, Japan 2 Department of Quantum Engineering and System Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-8656, Japan 3 Nuclear Professional School, School of Engineering, The University of Tokyo, Tokai-Mura, Naka-Gun 319-1188, Japan Correspondence should be addressed to Subas Chhatkuli, subas@nuclear.jp Received 22 September 2008; Revised 27 April 2009; Accepted 5 June 2009 Recommended by Ewa Pietka To reduce the side effects and to improve the efficiency of radiation therapy in lung cancer, a pinpoint radiation therapy system is under development. In the system, the movement of lung tumor during breathing could be estimated by employing a suitable numerical modeling technique. This paper presents a gridless numerical technique called Moving Particle Semi-implicit (MPS) method to simulate the lung deformation during breathing. The potential of the proposed method to employ in the future pinpoint radiation therapy system has been explored. Deformation of lung during breathing was dynamically tracked and compared against the experimental results at two different locations (upper lobe and lower lobe). Numerical simulations showed that the deformation of lung surface ranged from less than 4 mm to over 20 mm depending on the location at the surface of lung. The simulation showed that the lower section of lung exhibited comparatively large displaceme