effect of different vegetable oils (red palm olein, palm olein, corn oil and coconut oil) on lipid profile in rat影响不同的植物油(红棕榈油酸脂,椰子油精,玉米油和椰子油)在大鼠的血脂.pdfVIP
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effect of different vegetable oils (red palm olein, palm olein, corn oil and coconut oil) on lipid profile in rat影响不同的植物油(红棕榈油酸脂,椰子油精,玉米油和椰子油)在大鼠的血脂
Food and Nutrition Sciences, 2011, 2, 253-258
doi:10.4236/fns.2011.24036 Published Online June 2011 (/journal/fns)
Effect of Different Vegetable Oils (Red Palm Olein,
Palm Olein, Corn Oil and Coconut Oil) on Lipid
Profile in Rat
1 1 2 2
Eqbal Dauqan , Halimah Abdullah Sani , Aminah Abdullah , Zalifah Mohd Kasim
1School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi Selangor, Malaysia;
2School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi Selangor,
Malaysia.
Email: edouqan@, {halimah, kama, zalifahmk}@ukm.my
Received August 12th, 2010; revised February 26th, 2011; accepted March 3rd, 2011.
ABSTRACT
The objective of the study was to evaluate the effects of different vegetable oils [red palm olein (RPO), palm olein (PO),
corn oil (CO) and coconut oil (COC)] on lipid profile in rat. Sixty six Sprague Dawley male rats were randomly divided
into eleven groups of 6 rats per group and were treated with 15% concentrations of RPO, PO, CO and COC for 4 and 8
weeks. Rats in control group were given normal rat pellet only while in treated groups 15% of additional vegetable oils
were given. The results at 4 weeks showed a decline in Low Density Lipoprotein Cholesterol (LDL-C) values at RPO
and PO groups whereas in CO and COC groups the LDL-C were increased compared to the control group. The High
Density Lipoprotein Cholesterol (HDL-C) values increased in RPO and PO groups whereas it was declined in CO and
COC groups compared to the control group. At 8 weeks, there was no significant difference (P ≥ 0.05) in HDL-C of rats
treated with vegetable oils compared to the control group. However, the LDL-C in RPO and PO was significantly de-
creased (P ≤ 0.05) in the LDL-C and there was no significant difference
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