超声在中孕早期胎儿神经系统畸形中应用价值.docVIP

超声在中孕早期胎儿神经系统畸形中应用价值【摘要】 目的 探讨中孕早期超声检查对胎儿神经系统畸形的应用价值。方法 对中孕早期即12~18周进行超声检查的4150例孕妇的临床资料进行回顾性分析。结果 4150例产妇中经超声筛查检出并经引产证实的神经系统畸形21例，漏诊1例脊柱裂，神经系统畸形发生率为 0.53 %，检出率95.65%，其中脑积水1例，脊柱裂3例，全前脑畸形3例，脑膜脑膨出畸形4例，露脑畸形5例，无脑畸形儿6例，超声与产后的诊断符合率为100%。结论 中孕早期超声检查可对胎儿神经系统畸形做出正确诊断，为早期干预提供依据，同时可降低对孕妇生理、心理的伤害，对优生优育具有重要的作用。? 【关键词】 超声； 胎儿； 神经系统畸形； 中孕早期?? Ultrasound application value in the fetal nervous system malformation in the early-middle pregnancy ?LI Hui-lan,LI Jin,HU Wei. Shenzhen Nanshan Women and Children Health Care Hospital,Shenzhen 518054,China?? 【Abstract】 Objective To disscuss the ultrasound application value of nervous system malformation in the early-middle pregnancy.Methods The early stage of middle pregnancy to 12-18 weeks ultrasound examination of 4150 cases of clinical data of pregnant women were retrospectively analyzed.Results In 4150 cases of maternal screening detected by ultrasound and confirmed by the induction of 21 cases of nervous system malformation, 1 cases of missed diagnosis of spina bifida. Nervous system malformation rate of 0.53 percent, 95.65 percent detection rate, ultrasound diagnosis and post-natal diagnosis in line with the rate of 100%, of which six cases of anencephaly, five cases of exencephaly, four cases of meningoencephalocele,three cases of holoprosencephaly, three cases of spina bifida, one case of hydrocephalus.Conclusion Ultrasound in early-middle pregnancy in the nervous system of fetal malformation and make the correct diagnosis so that early intervention for children deformity, reduction of maternal physical and psychological harm, birth at the same time an important and irreplaceable role.? 【Key words】 Ultrasound； Fetal； Nervous system Malformation； Early-middle pregnancy ?? 神经系统先天畸形发生率较高，对人口素质的提高和社会经济的发展造成了重大影响，畸形儿中以神经管畸形最常见［1］，因此，近年来对此关注度越来越高［2］。这就要求必须寻找一种方便、快捷、安全且准确性高的筛查方法来筛查胎儿神经系统畸形。目前各家医院常规进行18～24周胎儿系统筛查，本院通过对4150例12～18周胎儿的超声检查发现，早期筛查出神经系统畸形并对其进行早期干预，可以减少孕妇生理和心理伤害，减少畸形儿出生，减少婴幼儿及围产儿死亡，达到提高出生人口质量，优生、优育的目的，现报道如下。? 1