bioassay-guided isolation and hplc determination of bioactive compound that relate to the antiplatelet activity (adhesion, secretion, and aggregation) from solanum lycopersicum获得隔离和高效液相色谱法测定生物活性化合物与抗血小板活动(附着力、分泌和聚合)从茄属植物lycopersicum.pdfVIP

Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2012, Article ID 147031, 10 pages doi:10.1155/2012/147031 Research Article Bioassay-Guided Isolation and HPLC Determination of Bioactive Compound That Relate to the Antiplatelet Activity (Adhesion, Secretion, and Aggregation) from Solanum lycopersicum Eduardo Fuentes,1, 2, 3 Ricardo Castro,3 Luis Astudillo,2, 3 Gilda Carrasco,2, 4 ´ 1, 2 ´ 2, 3 ´ 1, 2 Marcelo Alarcon, Margarita Gutierrez, and Ivan Palomo 1 Immunology and Haematology Laboratory, Immunohaematology and Clinical Biochemistry Department, Faculty of Health Sciences, Universidad de Talca, 3460000 Talca, Chile 2 Centro de Estudios en Alimentos Procesados (CEAP), CONICYT-Regional, Gore Maule, R09I2001 Talca, Chile 3 Synthesis Laboratory, Chemical Institute of Natural Resources, Universidad de Talca, 3460000 Talca, Chile 4 Horticulture Department, Faculty of Agricultural Sciences, Universidad de Talca, 3460000 Talca, Chile ´ ´ Correspondence should be addressed to Margarita Gutierrez, mgutierrez@utalca.cl and Ivan Palomo, ipalomo@utalca.cl Received 5 September 2012; Accepted 8 October 2012 Academic Editor: Adair Roberto Soares Santos Copyright © 2012 Eduardo Fuentes et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In seeking the functionality of foodstuff applicable to medicine, ripe tomato fruits were found to show an antiplatelet activit