the effect of cartilaginous rings on particle deposition by convection and brownian diffusion软骨环粒子沉积的影响通过对流和布朗扩散.pdfVIP

Vol.2, No.7, 769-779 (2010) Natural Science /10.4236/ns.2010.27097 The effect of cartilaginous rings on particle deposition by convection and Brownian diffusion 1 1 1 2 Hans O. Åkerstedt , Sofie M. Högberg , T. Staffan Lundström , Thomas Sandström 1Division of Fluid Mechanics, Luleå University of Technology, Luleå, Sweden; Sofie.Hogberg@ltu.se; staffan.lundstrom@ltu.se; Corresponding Author: hake@ltu.se 2Department of Public Health and Clinical Medicine, Division of Respiratory Medicine Allergy, Umeå University, Umeå, Sweden; thomas.sandstrom@lung.umu.se Received 26 March 2010; revised 11 May 2010; accepted 18 May 2010. ABSTRACT There is an increasing literature that discusses the ability of nanoparticles to cause adverse effects in cellular func- The deposition of spherical nanoparticles by tions [2]. Depending on the field of application, nano- convection and Brownian diffusion in a pipe particles may enter the body via inhalation, dermal, oral with a cartilaginous ring structure is studied. or injection exposure routes. Carbon nanotubes, for in- Analytical results for a fully developed flow are stance, have a diameter of approximately 10 nm with a found for small amplitude rings using the in-