the effect of dimiristoylphosphatidylethanol on the rotational mobility of n-(9-anthroyloxy) stearic acid in neuronal and model membranes的影响dimiristoylphosphatidylethanol旋转流动的n -(9-anthroyloxy)硬脂酸膜在神经元和模型.pdfVIP

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the effect of dimiristoylphosphatidylethanol on the rotational mobility of n-(9-anthroyloxy) stearic acid in neuronal and model membranes的影响dimiristoylphosphatidylethanol旋转流动的n -(9-anthroyloxy)硬脂酸膜在神经元和模型.pdf

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the effect of dimiristoylphosphatidylethanol on the rotational mobility of n-(9-anthroyloxy) stearic acid in neuronal and model membranes的影响dimiristoylphosphatidylethanol旋转流动的n -(9-anthroyloxy)硬脂酸膜在神经元和模型

Vol.1, No.3, 133-140 (2010) Journal of Biophysical Chemistry doi:10.4236/jbpc.2010.13016 The effect of dimiristoylphosphatidylethanol on the rotational mobility of n-(9-Anthroyloxy) stearic acid in neuronal and model membranes Young-Sik Park, No-Soo Park, Jun-Bong Seo, Soo-Kyoung Bae, You-Kwang kim, Ki-Soo Seong, Young-Jun Kim, Ju-Won Park, Joung-Moung Shin, Young-Chan Jeon, In-Kyo Chung, Moon-Kyoung Bae, Hye-Ock Jang*, Il Yun* School of Dentistry and Research Institute for Oral Biotechnology Pusan National University, Beomeo-ri, Mulgeum-eup, Yangsan, Gyeongsangnam-do, Korea; *Corresponding Author: iyun@pusan.ac.kr, jho9612@pusan.ac.kr Received 19 August 2010; revised 20 September 2010; accepted 25 September 2010. ABSTRACT lecular mechanism of action of ethanol, and include lipid [1-6], protein [7-13] and hydration [14-16] theories. The aim of this study was to provide a basis for However, the precise location of molecular action has examining the molecular mechanism for the continued to be a subject of controversy to the present pharmacological action of ethanol. We studied di- day. myristoylphosphatidylethanol (DMPEt)’s effects We have recently shown that a pathway of ethanol on specific locations of n-(9-anthroyloxy) palmitic metabolism with an unusual phospholipid, dimyristoyl-