changes of mind in an attractor network of decision-making改变心灵的吸引子网络的决策.pdfVIP

Changes of Mind in an Attractor Network of Decision-Making 1 1,2 Larissa Albantakis *, Gustavo Deco ´ 1 Department of Information and Communication Technologies, Computational Neuroscience, Universitat Pompeu Fabra, Barcelona, Spain, 2 Institucio Catalana de la Recerca i Estudis Avanc¸ats (ICREA), Universitat Pompeu Fabra, Barcelona, Spain Abstract Attractor networks successfully account for psychophysical and neurophysiological data in various decision-making tasks. Especially their ability to model persistent activity, a property of many neurons involved in decision-making, distinguishes them from other approaches. Stable decision attractors are, however, counterintuitive to changes of mind. Here we demonstrate that a biophysically-realistic attractor network with spiking neurons, in its itinerant transients towards the choice attractors, can replicate changes of mind observed recently during a two-alternative random-dot motion (RDM) task. Based on the assumption that the brain continues to evaluate available evidence after the initiation of a decision, the network predicts neural activity during changes of mind and accurately simulates reaction times, performance and percentage of changes dependent on difficulty. Moreover, the model suggests a low decision threshold and high incoming activity that drives the brain region involved in the decision-making process into a dynamical regime close to a bifurcation, which up to now lacked evidence for physiological relevance. Thereby, we further affirmed the general conformance of attractor networks with higher level neural processes and offe