characterization of a heme-regulated non-coding rna encoded by the prrf locus of pseudomonas aeruginosa描述的heme-regulated prrf轨迹的非编码rna编码的铜绿假单胞菌.pdfVIP

Characterization of a Heme-Regulated Non-Coding RNA Encoded by the prrF Locus of Pseudomonas aeruginosa Amanda G. Oglesby-Sherrouse*, Michael L. Vasil Department of Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America Abstract Pseudomonas aeruginosa, an opportunistic pathogen, requires iron for virulence and can obtain this nutrient via the acquisition of heme, an abundant source of iron in the human body. A surplus of either iron or heme can lead to oxidative stress; thus, the Fur (ferric uptake reg