dissection of the complex phenotype in cuticular mutants of arabidopsis reveals a role of serrate as a mediator解剖表皮复杂表型的突变体拟南芥的揭示了一个锯齿状的作为一个调停者的角色.pdfVIP

Dissection of the Complex Phenotype in Cuticular Mutants of Arabidopsis Reveals a Role of SERRATE as a Mediator 1 2 1¤a 3 ´ 1¤b Derry Voisin , Christiane Nawrath , Sergey Kurdyukov , Rochus B. Franke , Jose J. Reina-Pinto , 1¤c 1 3 1 Nadia Efremova , Isa Will , Lukas Schreiber , Alexander Yephremov * ¨ ¨ ¨ 1 Molekulare Pflanzengenetik, Max-Planck-Institut fur Zuchtungsforschung, Koln, Germany, 2 Department of Plant Molecular Biology, University of Lausanne, Lausanne, ¨ ¨ ¨ Switzerland, 3 Institut fur Zellulare and Molekulare Botanik, Universitat Bonn, Bonn, Germany Abstract Mutations in LACERATA (LCR), FIDDLEHEAD (FDH), and BODYGUARD (BDG) cause a complex developmental syndrome that is consistent with an important role for these Arabidopsis genes in cuticle biogenesis. The genesis of their pleiotropic phenotypes is, however, poorly understood. We provide evidence that neither distorted depositions of cutin, nor deficiencies in the chemical composition of cuticular lipids, account for these features, instead suggesting that the mutants alleviate the functional disorder of the cuticle by reinforcing their defenses. To better understand how plants adapt to these mutations, we performed a genome-wide gene expression analysis. We found that apparent compensatory transcriptional responses in these mutants involve