ecological adaptation of diverse honey bee (apis mellifera) populations生态适应多样化的蜜蜂蜜蜂()的人口.pdfVIP

Ecological Adaptation of Diverse Honey Bee (Apis mellifera) Populations 1 2 3 2 1 Robert Parker , Andony P. Melathopoulos , Rick White , Stephen F. Pernal , M. Marta Guarna , Leonard J. Foster1* 1 Centre for High-Throughput Biology and Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada, 2 Agriculture and Agri- Food Canada, Beaverlodge Research Farm, Beaverlodge, Canada, 3 Statistical Consulting and Research Laboratory, Department of Statistics, University of British Columbia, Vancouver, Canada Abstract Background: Honey bees are complex eusocial insects that provide a critical contribution to human agricultural food production. Their natural migration has selected for traits that increase fitness within geographical areas, but in parallel their domestication has selected for traits that enhance productivity and survival under local conditions. Elucidating the biochemical mechanisms of these local adaptive processes is a key goal of evolutionary biology. Proteomics provides tools unique among the major ‘omics disciplines for identifying the mechanisms employed by an organism in adapting to environmental challenges. Results: Through proteome profiling of adult honey bee midgut from geographically dispersed, domesticated populations combined with multiple parallel statistical treatments, the data presented here suggest some of the major cellular processes involved in adapting to different climates. These findings provide insight into the molecular underpinnings that may confer an advantage to honey bee populations. Significantly, the major energy-producing pathways of the mitochondria, the organelle most closely involved in heat production, were consistently higher in bees that