resting and dynamic electrocardiography in dogs with experimental chagas cardiomyopathy休息和动态心电描记法与实验狗恰加斯心肌病.pdfVIP

Hindawi Publishing Corporation Epidemiology Research International Volume 2012, Article ID 153539, 6 pages doi:10.1155/2012/153539 Research Article Resting and Dynamic Electrocardiography in Dogs with Experimental Chagas Cardiomyopathy R. Oliveira Alves,1 A. A. Camacho,2 and D. P. Junior2 1 Departamento de Medicina Veterinaria, Universidade Federal de Goias, Goiania, GO, Brazil ´ ´ ˆ 2 Departamento de Medicina e Cirurgia Veterinarias, UNESP, Jaboticabal, SP, Brazil ´ Correspondence should be addressed to R. Oliveira Alves, rosangela2210@ Received 21 March 2012; Revised 8 May 2012; Accepted 10 May 2012 Academic Editor: Alfonso J. Rodriguez-Morales Copyright © 2012 R. Oliveira Alves et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In the present protocol, adult dogs were infected with Trypanosoma cruzi, Bolivian strain, in order to show electrocardiographic changes by means of resting and dynamic (Holter) methods during acute and chronic phases of Chagas disease. In the acute phase there were sinus tachycardia, atrial and left ventricular overload, millivoltage suppression, electric alternance, and episodes of sinus arrest. At the parasitemia peak, atrium-ventricular block, junctional escape complexes, and atrium-ventricular dissociation were observed. Dogs that presented the most serious arrhythmias died suddenly. The increase in supraventricular and ventricular arrhythmic events, concentrated in the 4th postinoculation week, was visible at electrocar