solvent free interactions in contact pairs of molecules of biological interest laser spectroscopic and electrospray mass spectrometric studies溶剂自由交互接触对生物分子激光光谱和电喷雾质谱研究的兴趣.pdfVIP

Vol. 06 INTERNATIONAL JOURNAL OF PHOTOENERGY 2004 Solvent free interactions in contact pairs of molecules of biological interest: Laser spectroscopic and electrospray mass spectrometric studies D. Scuderi,1,2 A. Paladini,1 M. Satta,4 D. Catone,1 F. Rondino,1 A. Filippi,2 S. Piccirillo,3 M. Speranza,2 and A. Giardini Guidoni1,4,† 1 Dipartimento di Chimica, Università di Roma “La Sapienza”, pl. A. Moro 5, I-00185 Roma, Italy 2 Facoltà di Farmacia, Dipartimento di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università di Roma “La Sapienza”, pl. A. Moro 5, I-00185 Roma, Italy 3 Università di Roma “Tor Vergata” Dipartimento di Scienze e Tecnologie Chimiche, Via della Ricerca Scientifica, I-00133 Rome, Italy 4 CNR-IMIP (sezione Istituto Materiali Speciali), I-85050 Tito Scalo (Pz), Italy Abstract. A laser spectroscopic and mass spectrometric study of ionic and molecular clusters of biological interest is reported. The molecules of interest and their aggregates were generated in a supersonic beam and analyzed by mass resolved resonant two photon absorption and ionization (R2PI) and by collision induced mass spectrometry (CID-MS). The absence of the solvent allows to study these systems in the isolated state free of undesired solvent effects which may level off the differences in their properties. The gas phase results have been compared to theoretical estimates of the structure and stability of the systems under investigation. 1. INTRODUCTION Induced Dissociation (CID). The mass resolved R2PI