surgical treatment of peritoneal carcinomatosis from gastric cancer从胃癌手术治疗的腹膜癌扩散.pdfVIP

Hindawi Publishing Corporation International Journal of Surgical Oncology Volume 2012, Article ID 405652, 4 pages doi:10.1155/2012/405652 Review Article Surgical Treatment of Peritoneal Carcinomatosis from Gastric Cancer Kiran K. Turaga, T. Clark Gamblin, and Sam Pappas Division of Surgical Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, USA Correspondence should be addressed to Kiran K. Turaga, kturaga@ Received 6 February 2012; Accepted 11 May 2012 Academic Editor: Lapo Bencini Copyright © 2012 Kiran K. Turaga et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Peritoneal carcinomatosis from gastric cancer is considered a fatal disease with limited treatment options. Recent advances in the understanding of the disease process, systemic chemotherapy, and application of cytoreductive surgery and hyperthermic chemoperfusion have shown promising results in the management of this difficult disease. Novel therapies such as extensive intraperitoneal lavage and intraperitoneal targeted agents are being applied in the management of this disease. We review the current literature in this field and describe the rationale behind some of these advances. 1. Introduction demonstrated an effective use of multimodality therapy for patients with gastric cancer. Gastric cancer is the second leading cause for cancer-related mortality worldwide with almost 22,280 patients being The application of hyperthermic intraperitoneal chemo- diagnosed with gastric cancer annua