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a survey on infection management practices in italian icus一项调查在意大利icu感染管理实践
Bassetti et al. Critical Care 2012, 16:R221
/content/16/6/R221
RESEARCH Open Access
A survey on infection management practices in
Italian ICUs
1* 2 3 4 5 6
Matteo Bassetti , Raffaele De Gaudio , Teresita Mazzei , Giulia Morace , Nicola Petrosillo , Pierluigi Viale ,
Giuseppe Bello7, Sofia La Face8 and Massimo Antonelli7
Abstract
Introduction: An online survey was conducted to characterize current infection management practices in Italian
intensive care units (ICUs), including the antibacterial and antifungal drug regimens prescribed for various types of
infections.
Methods: During February and March 2011, all 450 ICUs in public hospitals in Italy were invited to take part in an
online survey. The questionnaire focused on ICU characteristics, methods used to prevent, diagnose, and treat
infections, and antimicrobials prescribing policies. The frequency of each reported practice was calculated as a
percentage of the total number of units answering the question. The overall response rate to the questionnaire
was 38.8% (175 of the 450 ICUs contacted) with homogeneous distribution across the country and in terms of unit
type.
Results: Eighty-eight percent of the responding facilities performed periodical surveillance cultures on all patients.
In 71% of patients, cultures were also collected on admission. Endotracheal/bronchial aspirates were the most
frequently cultured specimens at both time points. Two-thirds of the responding units had never performed
screening cultures for methicillin-resistant Staphylococcus aureus. Around 67% of the ICUs reported the use of
antimicrobial de-escalation strategies during the treatment phase. In general, the use of empirical antimicrobial
drug reg
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