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注射用阿莫西林钠舒巴坦钠(Amoxicillin Sodium and Sulbactam Sodium for Injection)
注射用阿莫西林钠舒巴坦钠(Amoxicillin Sodium and Sulbactam Sodium for Injection)
Amoxicillin Sodium and Sulbactam Sodium for Injection (Amoxicillin, Sodium, and, Injection, Sulbactam, Sodium, for, etc)
(Sidilin, Shu Salin, Xiao Fei)
This product is a compound preparation, the group divided into amoxicillin sodium and sulbactam sodium. Their chemical names are:
Amo Shilling Na: (2S, 5R, 6R) -3, 3-, two methyl, -6-[(R) - - (-) -2-, amino -2- (4- hydroxy phenyl) - acetyl]-7-, oxo -4-, sulfur hetero -1-, aza [3.2.0], heptane, -2-, sodium formate.
Chuba Staw Na: (2S, 5R) -3, 3- two methyl -7- oxo -4- -1- dithia aza bicyclo [3.2.0] heptane -2- carboxylic acid sodium -4, 4- dioxide.
[traits]
This product is white or white powder. After dissolving, the solution is colorless or pale yellow.
[pharmacology and toxicology]
pharmacological action
This compound is composed of amoxicillin sodium and sulbactam sodium. Department of amoxicillin bactericidal broad-spectrum antibiotics, sulbactam system irreversible broad-spectrum beta lactamase inhibitor, can effectively inhibit bacteria produce beta lactamase. Clinically, many gram positive and gram negative bacteria produce beta lactamase, which can cause amoxicillin to lose its antibacterial activity. Because there can be amoxicillin sulbactam sodium, from p- lactamase destruction, which has produced beta lactamase producing bacteria resistant to amoxicillin, still susceptible to amoxicillin.
This product is bactericidal antibiotic, in clinical can kill a variety of gram positive and gram negative bacteria, especially for beta lactamase producing bacteria have curative effect, these bacteria include:
Gram-positive bacteria:
Aerobic bacteria: Staphylococcus aureus, fecal streptococci, Staphylococcus epidermidis, monocytes, gram positive bacteria, Streptococcus pyogenes, Corynebacterium, green green Streptococcus, Streptococcus pneumoniae.
Anaerobic bacteria: Clostridium, digestive, Streptococcus, and digestive cocci.
Gram negative bacteria:
Aer
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