albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure白蛋白透析改善肝性脑病和降低酒精性肝炎患者循环酚醛芳香族氨基酸和严重肝功能衰竭.pdfVIP

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albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure白蛋白透析改善肝性脑病和降低酒精性肝炎患者循环酚醛芳香族氨基酸和严重肝功能衰竭.pdf

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albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure白蛋白透析改善肝性脑病和降低酒精性肝炎患者循环酚醛芳香族氨基酸和严重肝功能衰竭

Available online /content/13/1/R8 Vol 13 No 1 Open Access Research Albumin dialysis improves hepatic encephalopathy and decreases circulating phenolic aromatic amino acids in patients with alcoholic hepatitis and severe liver failure Albert Parés, Ramón Deulofeu, Laura Cisneros, Angels Escorsell, Joan Manuel Salmerón, Joan Caballería and Antoni Mas Liver Unit, Digestive Diseases Institute. Hospital Clínic, Centro de Investigaciones Biomédicas en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut dInvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/. Villarroel 170, Barcelona, 08036, Spain Corresponding author: Albert Parés, pares@ Received: 28 Nov 2008 Revisions requested: 8 Jan 2009 Revisions received: 22 Jan 2009 Accepted: 28 Jan 2009 Published: 28 Jan 2009 Critical Care 2009, 13:R8 (doi:10.1186/cc7697) This article is online at: /content/13/1/R8 © 2009 Parés et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction The aim of this study was to assess the effects of 0.02), and a decrease in total amino acid levels (2490 ± 152 μM albumin dialysis on hepatic encephalopathy and circulating to 2229 ± 114 μM, p 0.001). Moreover, the Fischers ratio, levels of amino acids in severe alcoholic hepatitis. which was significantly lower in patients with alcoholic hepatitis (1.32 ± 0.08) than in controls (3.20 ± 0.16), increased b