reproductive status is associated with the severity of fibrosis in women with hepatitis c生殖状态与女性丙型肝炎纤维化的严重程度.pdfVIP

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reproductive status is associated with the severity of fibrosis in women with hepatitis c生殖状态与女性丙型肝炎纤维化的严重程度.pdf

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reproductive status is associated with the severity of fibrosis in women with hepatitis c生殖状态与女性丙型肝炎纤维化的严重程度

Reproductive Status Is Associated with the Severity of Fibrosis in Women with Hepatitis C 1 1 ` 2 2 3 1 Erica Villa *, Ranka Vukotic , Calogero Camma , Salvatore Petta , Alfredo Di Leo , Stefano Gitto , 1 1 4 1 5 Elena Turola , Aimilia Karampatou , Luisa Losi , Veronica Bernabucci , Annamaria Cenci , 5 5 1 6 1 Simonetta Tagliavini , Enrica Baraldi , Nicola De Maria , Roberta Gelmini , Elena Bertolini , Maria Rendina3, Antonio Francavilla7 1 Department of Gastroenterology, Azienda Ospedaliero-Universitaria University of Modena and Reggio Emilia, Modena, Italy, 2 Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Palermo, Italy, 3 Department of Gastroenterology, University of Bari, Bari, Italy, 4 Department of Pathology, Azienda Ospedaliero-Universitaria, Modena, Italy, 5 Department of Clinical Pathology, NOCSAE, Modena, Italy, 6 Department of General Surgery, Azienda Ospedaliero-Universitaria, Modena, Italy, 7 Istituto di Ricovero e Cura ‘‘Saverio de Bellis’’, Castellana Grotte, Italy Abstract Introduction: Chronic hepatitis C is the main cause of death in patients with end-stage liver disease. Prognosis depends on the increase of fibrosis, whose progression is twice as rapid in men as in women. Aim of the study was to evaluate the effects of reproductive stage on fibrosis severity in women and to compare these findings with age-matched men. Material