restriction of hiv-1 genotypes in breast milk does not account for the population transmission genetic bottleneck that occurs following transmission限制hiv - 1基因型在母乳不占人口传播遗传瓶颈后发生传播.pdfVIP

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restriction of hiv-1 genotypes in breast milk does not account for the population transmission genetic bottleneck that occurs following transmission限制hiv - 1基因型在母乳不占人口传播遗传瓶颈后发生传播.pdf

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restriction of hiv-1 genotypes in breast milk does not account for the population transmission genetic bottleneck that occurs following transmission限制hiv - 1基因型在母乳不占人口传播遗传瓶颈后发生传播

Restriction of HIV-1 Genotypes in Breast Milk Does Not Account for the Population Transmission Genetic Bottleneck That Occurs following Transmission 1. 2. 2 3 2,4 2¤ Laura Heath , Susan Conway , Laura Jones , Katherine Semrau , Kyle Nakamura , Jan Walter , W. 2 2 2 5 6 7 Don Decker , Jason Hong , Thomas Chen , Marintha Heil , Moses Sinkala , Chipepo Kankasa , 3 8 1,9 2 Donald M. Thea , Louise Kuhn , James I. Mullins , Grace M. Aldrovandi * 1 Department of Microbiology, University of Washington, Seattle, Washington, United States of America, 2 Childrens Hospital of Los Angeles, Los Angeles, California, United States of America, 3 Boston University School of Public Health, Boston, Massachusetts, United States of America, 4 University of Southern California Keck School of Medicine, Los Angeles, California, United States of America, 5 Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, 6 Lusaka District Health Management Team, Lusaka, Zambia, 7 University Teaching Hospital, University of Zambia, Lusaka, Zambia, 8 Columbia University, New York, New York, United States of America, 9 Department of Medicine, University of Washington, Seattle, Washington, United States of America Abstract Background: Breast milk transmission of HIV-1 remains a major route of pediatric infection. Defining the characteristics of viral variants to which breastfeeding infants are exposed is important for u