risk factors for ocular chlamydia after three mass azithromycin distributions眼衣原体感染的风险因素三质量阿奇霉素后分布.pdfVIP

Risk Factors for Ocular Chlamydia after Three Mass Azithromycin Distributions 1 1 2 3 3 3 Berhan Ayele , Teshome Gebre , Jeanne Moncada , Jenafir I. House , Nicole E. Stoller , Zhaoxia Zhou , 3,4,5 3,4 6 2 3,4 Travis C. Porco , Bruce D. Gaynor , Paul M. Emerson , Julius Schachter , Jeremy D. Keenan * 1The Carter Center, Addis Ababa, Ethiopia, 2 Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America, 3 F.I. Proctor Foundation, University of California San Francisco, San Francisco, California, United States of America, 4 Department of Ophthalmology, University of California San Francisco, San Francisco, California, United States of America, 5 Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America, 6 The Carter Center, Atlanta, Georgia, United States of America Abstract Background: An important component of the World Health Organization’s comprehensive trachoma elimination strategy is the provision of repeated annual mass azithromycin distributions, which are directed at reducing the burden of ocular chlamydia. Knowledge of characteristics associated with infection after mass antibiotic treatments could allow trachoma programs to focus resources to those most likely to be infected with ocular chlamydia. Methodology/Principal Findings: We monitored 12 communities in rural Ethiopia that had received 3 annual mass azithromycin treat