原创力文档risk factors for helminth, malaria, and hiv infection in pregnancy in entebbe, uganda寄生虫的危险因素、疟疾、在乌干达恩德培和艾滋病毒感染在怀孕.pdfVIP
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risk factors for helminth, malaria, and hiv infection in pregnancy in entebbe, uganda寄生虫的危险因素、疟疾、在乌干达恩德培和艾滋病毒感染在怀孕
Risk Factors for Helminth, Malaria, and HIV Infection in
Pregnancy in Entebbe, Uganda
1 1 2 1
Patrick William Woodburn *, Lawrence Muhangi , Stephen Hillier , Juliet Ndibazza , Proscovia Bazanya
1 1 1 1 3
Namujju , Moses Kizza , Christine Ameke , Nicolas Emojong Omoding , Mark Booth , Alison Mary
Elliott1,4
1 MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda, 2 University of Birmingham, Birmingham, United Kingdom, 3 University of Durham, Durham, United
Kingdom, 4 London School of Hygiene and Tropical Medicine, London, United Kingdom
Abstract
Background: Infections during pregnancy may have serious consequences for both mother and baby. Assessment of risk
factors for infections informs planning of interventions and analysis of the impact of infections on health outcomes.
Objectives: To describe risk factors for helminths, malaria and HIV in pregnant Ugandan women before intervention in a
trial of de-worming in pregnancy.
Methods: The trial recruited 2,507 pregnant women between April 2003 and November 2005. Participants were interviewed
and blood and stool samples obtained; location of residence at enrolment was mapped. Demographic, socioeconomic,
behavioral and other risk factors were modelled using logistic regression.
Results: There was a high prevalence of helminth, malaria and HIV infection, as previously reported. All helminths and
malaria parasitemia were more common in younger women, and education was protective against every infection. Place of
birth and/or tribe affected all helminths in a pattern consistent with the geographical distribution of helminth infections in
Uganda.
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