automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring自动化in-silico检测细胞群在流式细胞仪读数和白血病疾病监测的应用.pdfVIP

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automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring自动化in-silico检测细胞群在流式细胞仪读数和白血病疾病监测的应用.pdf

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automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring自动化in-silico检测细胞群在流式细胞仪读数和白血病疾病监测的应用

BMC Bioinformatics BioMed Central 2Research article Open Access Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring 1,3 2 2 2 Joern Toedling , Peter Rhein , Richard Ratei , Leonid Karawajew and Rainer Spang*1 Address: 1Max Planck Institute for Molecular Genetics Berlin Center for Genome Based Bioinformatics, Ihnestrasse. 73, D-14195 Berlin, Germany, 2Dept. of Hematology, Oncology and Tumor Immunology, Robert-Roessle-Clinic at the HELIOS Klinikum Berlin, Charité Medical School, Berlin, Germany and 3EMBL – European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK Email: Joern Toedling - toedling@ebi.ac.uk; Peter Rhein - rhein@rrk.charite-buch.de; Richard Ratei - rratei@berlin.helios-kliniken.de; Leonid Karawajew - karawajew@rrk.charite-buch.de; Rainer Spang* - spang@molgen.mpg.de * Corresponding author Published: 05 June 2006 Received: 13 January 2006 Accepted: 05 June 2006 BMC Bioinformatics 2006, 7:282 doi:10.1186/1471-2105-7-282 This article is available from: /1471-2105/7/282 © 2006 Toedling et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Identification of minor cell populati