interferon-induced protein ifit4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells干扰素诱导蛋白ifit4与系统性红斑狼疮和促进单核细胞向树突状细胞样的细胞的分化.pdfVIP
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interferon-induced protein ifit4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells干扰素诱导蛋白ifit4与系统性红斑狼疮和促进单核细胞向树突状细胞样的细胞的分化
Available online /content/10/4/R91
Vol 10 No 4 Open Access
Research article
Interferon-induced protein IFIT4 is associated with systemic lupus
erythematosus and promotes differentiation of monocytes into
dendritic cell-like cells
1,2 1,2 1 1 3 1
Xiangyang Huang , Nan Shen , Chunde Bao , Yueying Gu , Li Wu and Shunle Chen
1Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shan Dong Middle Road, Shanghai 200001,
PR China
2Molecular Rheumatology Laboratory, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and
Shanghai Jiao Tong University School of Medicine, Chong Qing South Road, Shanghai 200025, PR China
3Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Royal Parade, Parkville, Victoria 3050, Australia
Corresponding author: Nan Shen, shennand@
Received: 22 Feb 2008 Revisions requested: 8 Apr 2008 Revisions received: 4 Aug 2008 Accepted: 15 Aug 2008 Published: 15 Aug 2008
Arthritis Research Therapy 2008, 10:R91 (doi:10.1186/ar2475)
This article is online at: /content/10/4/R91
© 2008 Huang et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction Using oligonucleotide microarray, many IFN- localized exclusively to the cytoplasm, and it was significantly
inducible gene
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