interindividual and intercellular polymorphisms of ag-nor pattern in mink embryo siblings个人间和细胞间多态性ag-nor模式貂胚胎的兄弟姐妹.pdfVIP

Original article Interindividual and intercellular polymorphisms of Ag-NOR pattern in mink embryo siblings GK Isakova Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, 630090 Novosibirsk, Russia (Received 24 February 1993; accepted 19 May 1994) Summary - The variability of the silver-staining pattern of the nucleolus organizing regions (Ag-NOR pattern) was studied in hepatocytes from 9 mink embryo siblings, including a pair of monochorionic (presumably monozygotic) co-twins. Both the number of Ag-NORs and the mean size of Ag-spots per cell were found to be identical in monochorionic twins. All other sibs had patterns different from each other and from co-twins. Intercellular variation of both the number and size of Ag-stained regions, as measured by the coefficient of variation, was similar only in monochorionic twins. The data indicate that both the interindividual and intercellular variations of the Ag-NOR pattern are highly heritable. The mechanisms underlying the Ag-NOR pattern polymorphisms are discussed. It is proposed that at least 2 independently inherited routes for the variable expression of the ribosomal gene system exist: 1) polymorphism for rDNA array; and 2) polymorphism for rRNA gene expression. mink / embryo / chromosome / nucleolus organizing region / silver staining Résumé - Polymorphisme interindividuel et intercellulaire de la coloration à l’argent des régions des organisateurs nucléolaires chez des embryons de vison. La variabilité de la coloration à l’argent des régions des organisateurs nucléolaires (Ag-NOR) a été étudiée sur des hépatocytes de 9 embryons de vison, germains de portée et incluant une paire de jumeaux monochorioniques, présumés monozygotes. À la fois le