pediatric functional magnetic resonance neuroimaging tactics for encouraging task compliance小儿功能性磁共振神经成像策略鼓励合规的任务.pdfVIP

Schlund et al. Behavioral and Brain Functions 2011, 7:10 /content/7/1/10 RESEARCH Open Access Pediatric functional magnetic resonance neuroimaging: tactics for encouraging task compliance 1,2,3,4* 2,3 1,5 1 1,5 Michael W Schlund , Michael F Cataldo , Greg J Siegle , Cecile D Ladouceur , Jennifer S Silk , 1,5 1 6 1 1 Erika E Forbes , Ashley McFarland , Satish Iyengar , Ronald E Dahl and Neal D Ryan Abstract Background: Neuroimaging technology has afforded advances in our understanding of normal and pathological brain function and development in children and adolescents. However, noncompliance involving the inability to remain in the magnetic resonance imaging (MRI) scanner to complete tasks is one common and significant problem. Task noncompliance is an especially significant problem in pediatric functional magnetic resonance imaging (fMRI) research because increases in noncompliance produces a greater risk that a study sample will not be representative of the study population. Method: In this preliminary investigation, we describe the development and application of an approach for increasing the number of fMRI tasks children complete during neuroimaging. Twenty-eight healthy children ages 9- 13 years participated. Generalization of the approach was examined in additional fMRI and event-related potential investigations with children at risk for depression, children with anxiety and children with depression (N = 120). Essential features of the approach include a preference assessment for identifying multiple individualized rewards, increasing reinforcement rates during