原创力文档plasma cell disorders in hiv-infected patients epidemiology and molecular mechanisms浆细胞疾病感染艾滋病毒的患者的流行病学和分子机制.pdfVIP
- 1、本文档共12页，可阅读全部内容。
- 2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
- 3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
plasma cell disorders in hiv-infected patients epidemiology and molecular mechanisms浆细胞疾病感染艾滋病毒的患者的流行病学和分子机制
Coker et al. Biomarker Research 2013, 1:8
/content/1/1/8
REVIEW Open Access
Plasma cell disorders in HIV-infected patients:
epidemiology and molecular mechanisms
*
Woodrow J Coker, Ashley Jeter, Henning Schade and Yubin Kang
Abstract
Highly active antiretroviral therapy (HAART) has significantly improved the outcome and survival of human
immunodeficiency virus (HIV)-infected patients. Subsequently, long-term morbidities including cancer have become
of major public health and clinical interest for this patient population. Plasma cell disorders occur at higher
incidence in HIV-infected patients; however, the molecular mechanisms driving the plasma cell disease process and
the optimal management for these patients remain to be defined. This article provides an up-to-date review of the
characteristics and management of HIV-infected patients with plasma cell disorders. We first present 3 cases of
plasma cell disorders in HIV-infected patients, ranging from polyclonal hypergammaglobulinemia to symptomatic
multiple myeloma. We then discuss the epidemiology, clinical presentation, and management of each of these
plasma cell disorders, with an emphasis on the molecular events underlying the progression of plasma cell diseases
from monoclonal gammopathy to symptomatic multiple myeloma. We propose a three-step hypothesis for the
development of multiple myeloma. Finally, we discuss the use of high dose chemotherapy and autologous
hematopoietic stem cell transplantation in the treatment of HIV-infected patients with multiple myeloma. Our
review includes the care of HIV-infected patients with plasma cell disorders in the current era of HAART and novel
agents available for the treatment of multiple myeloma.
Keywords: HIV, AIDS, Gammopa
您可能关注的文档
- phenolic content and antioxidant activity of hibiscus cannabinus l. seed extracts after sequential solvent extraction酚含量和抗氧化活性的芙蓉cannabinus l .顺序溶剂萃取后种子提取物.pdf
- phenolic compounds in brassica vegetables酚类化合物在甘蓝类蔬菜.pdf
- phenolic compounds from allium schoenoprasum, tragopogon pratensis and rumex acetosa and their antiproliferative effects酚类化合物从葱属schoenoprasum tragopogon pratensis和rumex acetosa及其抗增殖效果.pdf
- phenolic enriched extract of baccharis trimera presents anti-inflammatory and antioxidant activities酚醛浓缩提取物baccharis trimera礼物抗炎和抗氧化活动.pdf
- phenolic compounds in field horsetail (equisetum arvense l.) as natural antioxidants酚类化合物在马尾(木贼属arvense l .)作为天然的抗氧化剂.pdf
- phenolic-compound-extraction systems for fruit and vegetable samples水果和蔬菜样品phenolic-compound-extraction系统.pdf
- phenolic profiles and antioxidant activity of litchi (litchi chinensis sonn.) fruit pericarp from different commercially available cultivars酚醛概要文件和抗氧化活性的荔枝(荔枝比如说)。.pdf
- phenolics occurrence and immunochemical detection in environment and food酚醛树脂发生和免疫化学检测在环境和食品.pdf
- phenolics from chemistry to biology酚醛树脂化学生物学.pdf
- phenolic molecules in virgin olive oils a survey of their sensory properties, health effects, antioxidant activity and analytical methods. an overview of the last decade alessandra酚醛树脂分子初榨橄榄油的调查他们的感官性状,健康的影响、抗氧化活性和分析方法。.pdf
- plasma cell-free dna in patients needing mechanical ventilation血浆游离dna的病人需要机械通气.pdf
- plasma concentrations of cortisol and pgf2α metabolite in danish sows during mating, and intrauterine and conventional insemination血浆皮质醇浓度和pgf2α代谢物在丹麦母猪交配,传统和子宫内受精.pdf
- plasma dna concentration as a predictor of mortality and sepsis in critically ill patients等离子体dna浓度的预测危重患者的死亡率和败血症.pdf
- plasma concentrations of soluble cytokine receptors in euthymic bipolar patients with and without subsyndromal symptoms等离子体浓度的可溶性细胞因子受体euthymic双相患者和没有亚综合征症状.pdf
- plasma calcium, inorganic phosphate and magnesium during hypocalcaemia induced by a standardized edta infusion in cows血浆钙、无机磷和镁在奶牛标准化edta注入引起的低钙血症.pdf
- plasma cytokine profiles in systemic sclerosis associations with autoantibody subsets and clinical manifestations血浆细胞因子在系统性硬化协会自身抗体子集和临床表现.pdf
- plasma depolymerization of chitosan in the presence of hydrogen peroxide等离子体解聚壳聚糖的过氧化氢的存在.pdf
- plasma charge current for controlling and monitoring electron beam welding with beam oscillation等离子体电流控制和监测电子束焊接梁振荡.pdf
- plasma kallistatin levels in patients with severe community-acquired pneumonia例如社区获得性肺炎患者的血浆kallistatin水平严重.pdf
- plasma concentrations of gas6 (growth arrest specific protein 6) and its soluble tyrosine kinase receptor saxl in sepsis and systemic inflammatory response syndromes等离子体浓度gas6(增长逮捕特定蛋白质6)及其可溶性酪氨酸激酶受体saxl在脓毒症和系统性炎症反应综合征.pdf
文档评论（0）