procon debate is intensive insulin therapy targeting tight blood glucose control of benefit in critically ill patients圣保罗市辩论是强化胰岛素治疗的严格的血糖控制目标危重患者受益.pdfVIP
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procon debate is intensive insulin therapy targeting tight blood glucose control of benefit in critically ill patients圣保罗市辩论是强化胰岛素治疗的严格的血糖控制目标危重患者受益
Available online /content/12/2/212
Review
Pro/con debate: Is intensive insulin therapy targeting tight blood
glucose control of benefit in critically ill patients?
Tobias M Merz and Simon Finfer
Department of Intensive Care Medicine, Royal North Shore Hospital of Sydney, St Leonards, 2065 NSW, Australia
Corresponding author: Simon Finfer, sfinfer@.au
Published: 25 April 2008 Critical Care 2008, 12:212 (doi:10.1186/cc6837)
This article is online at /content/12/2/212
© 2008 BioMed Central Ltd
Abstract failure and cardiogenic shock after myocardial infarction [20].
You have decided to develop a protocol for insulin therapy in your In summary, hyperglycaemia is common in critically ill patients
intensive care unit (ICU). You wonder about the merit of using and its occurrence is clearly associated with a worse
intensive insulin therapy (IIT) to maintain tight blood glucose outcome; thus, it is natural to ask whether hyperglycaemia is
control in your patients. simply a marker of illness severity, or is hyperglycaemia itself
harmful, in which case does normalizing blood glucose
Pro: Intensive insulin therapy targeting tight improve patients’ outcomes?
blood glucose control is of benefit in critically
ill patients The evidence that short-term treatment of hyperglycaemia is
Hyperglycaemia is a common accompaniment of acute beneficial in acute illness
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