quantification of damage in dna recovered from highly degraded samples – a case study on dna in faeces量化损伤dna从高度退化中恢复过来u2014u2014一个案例研究在粪便的dna样本.pdfVIP

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quantification of damage in dna recovered from highly degraded samples – a case study on dna in faeces量化损伤dna从高度退化中恢复过来u2014u2014一个案例研究在粪便的dna样本.pdf

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quantification of damage in dna recovered from highly degraded samples – a case study on dna in faeces量化损伤dna从高度退化中恢复过来u2014u2014一个案例研究在粪便的dna样本

Frontiers in Zoology BioMed Central Methodology Open Access Quantification of damage in DNA recovered from highly degraded samples – a case study on DNA in faeces 1,2 3 2 Bruce E Deagle* , J Paige Eveson and Simon N Jarman Address: 1School of Zoology, University of Tasmania, Box 252-05, Hobart, Tasmania, Australia, 2Australian Antarctic Division, Channel Highway, Kingston, Tasmania, Australia and 3CSIRO Marine and Atmospheric Research, Box 1538, Hobart, Tasmania, Australia Email: Bruce E Deagle* - bedeagle@.au; J Paige Eveson - paige.eveson@csiro.au; Simon N Jarman - simon.jarman@.au * Corresponding author Published: 16 August 2006 Received: 13 May 2006 Accepted: 16 August 2006 Frontiers in Zoology 2006, 3:11 doi:10.1186/1742-9994-3-11 This article is available from: /content/3/1/11 © 2006 Deagle et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Poorly preserved biological tissues have become an important source of DNA for a wide range of zoological studies. Measuring the quality of DNA obtained from these samples is often desired; however, there are no widely used techniques available for quantifying damage in highly degraded DNA samples. We pr