relation between pro-inflammatory cytokines and acetylcholine levels in relapsing-remitting multiple sclerosis patients促炎细胞因子之间的关系和乙酰胆碱水平复发缓和多发性硬化患者.pdfVIP

Int. J. Mol. Sci. 2012, 13, 12656-12664; doi:10.3390/ijms131012656 OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Relation between Pro-inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients Marcella Reale 1,*, Federica de Angelis 2, Marta di Nicola 1, Elisabetta Capello 3, Maria di Ioia 4, Giovanna de Luca 4, Alessandra Lugaresi 4 and Ada Maria Tata 2,* 1 Department of Experimental and Clinical Sciences, University “G. d’Annunzio” Chieti-Pescara, Via Dei Vestini, 31 66100 Chieti, Italy; E-Mail: m.dinicola@unich.it 2 Department of Biology and Biotechnologies Charles Darwin, Sapienza, University of Rome, Research Center of Neurobiology D. Bovet, P.le Aldo Moro, 5 00185 Roma, Italy; E-Mail: federica.deangelis@uniroma1.it 3 Department of Neuroscience, Ophthalmology and Genetics, University of Genova, 16126 Genova, Italy; E-Mail: ecapello@neurologia.unige.it 4 Department of Neuroscience and Imaging, University “G. d’Annunzio” Chieti-Pescara, 66100 Chieti, Italy; E-Mail: a.lugaresi@unich.it (A.L.) * Authors to whom correspondence should be addressed; E-Mails: mreale@unich.it (M.R.); adamaria.tata@uniroma1.it (A.M.T.); Tel.: +39-0871-355-4029 (M.R.); +39-06(A.M.T.); Fax: +39-0871-355-4029 (M.R.); +39-06(A.M.T.). Received: 1 August 2012; in revised form: 6 September 2012 / Accepted: 27 September 2012 / Published: 3 October 2012 Abstract: Multiple sclerosis (MS)