risk and prognostic factors of inpatient mortality associated with unintentional insecticide and herbicide poisonings a retrospective cohort study风险和住院病人死亡率的预后因素与无意的杀虫剂和除草剂中毒回顾性队列研究.pdfVIP

Risk and Prognostic Factors of Inpatient Mortality Associated with Unintentional Insecticide and Herbicide Poisonings: A Retrospective Cohort Study 1 2 3 1 1 Wu-Chien Chien , Chi-Hsiang Chung , Jouni J. K. Jaakkola , Chi-Ming Chu , Senyeong Kao , Sui- 1 1 Lung Su , Ching-Huang Lai * 1 Department of Public Health, National Defense Medical Center, No. 161, Section 6, Neihu District, Taipei City, Taiwan, Republic of China, 2 Graduate Institute of Life Sciences, National Defense Medical Center, No. 161, Section 6, Neihu District, Taipei City, Taiwan, Republic of China, 3 Center for Environmental and Respiratory Health Research, Institute of Health Sciences, University of Oulu, Oulu, Finland Abstract Introduction: Pesticide poisoning is an important public health problem worldwide. The study aimed to determine the risk of all-cause and cause-specific inpatient mortality and to identify prognostic factors for inpatient mortality associated with unintentional insecticide and herbicide pesticide poisonings. Methods: We performed a retrospective cohort study of 3,986 inpatients recruited at hospitalization between 1999 and 2008 in Taiwan. We used the International Classification of Disease, 9th ed., Clinical Modification external causes of injury codes to classify poisoning agents into accidental poisoning by insecticides and herbicides. Comparisons in mortality rates were made between insecticide poisoning patients and herbicide poisoning patients by using the Cox proportional hazards models to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs). Results: There were 168 deaths during 21,583 person-days of follow-up evaluation (7.8 per 1,000 person-days). The major causes of mor