原创力文档risk assessment of pm2.5 to child residents in brazilian amazon region with biofuel production风险评估的pm2.5的孩子在巴西亚马逊地区居民与生物燃料生产.pdfVIP
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risk assessment of pm2.5 to child residents in brazilian amazon region with biofuel production风险评估的pm2.5的孩子在巴西亚马逊地区居民与生物燃料生产
de Oliveira et al. Environmental Health 2012, 11:64
/content/11/1/64
RESEARCH Open Access
Risk assessment of PM2.5 to child residents in
Brazilian Amazon region with biofuel production
1* 2,3 4 5†
Beatriz Fátima Alves de Oliveira , Eliane Ignotti , Paulo Artaxo , Paulo Hilário do Nascimento Saldiva ,
Washington Leite Junger6† and Sandra Hacon1†
Abstract
Background: Exposure to fine fractions of particulate matter (PM2.5) is associated with increased hospital
admissions and mortality for respiratory and cardiovascular disease in children and the elderly. This study aims to
estimate the toxicological risk of PM2.5 from biomass burning in children and adolescents between the age of 6
and 14 in Tangará da Serra, a municipality of Subequatorial Brazilian Amazon.
Methods: Risk assessment methodology was applied to estimate the risk quotient in two scenarios of exposure
according to local seasonality. The potential dose of PM2.5 was estimated using the Monte Carlo simulation,
stratifying the population by age, gender, asthma and Body Mass Index (BMI).
Results: Male asthmatic children under the age of 8 at normal body rate had the highest risk quotient among the
subgroups. The general potential average dose of PM2.5 was 1.95 μg/kg.day (95% CI: 1.62 – 2.27) during the dry
scenario and 0.32 μg/kg.day (95% CI: 0.29 – 0.34) in the rainy scenario. During the dry season, children and
adolescents showed a toxicological risk to PM2.5 of 2.07 μg/kg.day (95% CI: 1.85 – 2 .30).
Conclusions: Children and adolescents living in the Subequatorial Brazilian Amazon region were exposed to high
levels of PM2.5 resulting in toxicological risk for this multi-pollutant. The toxicologic
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