safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis安全评估drotrecogin阿尔法(激活)治疗成人严重脓毒症患者.pdfVIP

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safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis安全评估drotrecogin阿尔法(激活)治疗成人严重脓毒症患者.pdf

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safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis安全评估drotrecogin阿尔法(激活)治疗成人严重脓毒症患者

Available online /content/7/2/155 Research Open Access Safety assessment of drotrecogin alfa (activated) in the treatment of adult patients with severe sepsis 1 2 3 3 4 Gordon R Bernard , William L Macias , David E Joyce , Mark D Williams , Joan Bailey and Jean-Louis Vincent5 1Director, Division of Allergy, Pulmonary and Critical Care, Vanderbilt University School of Medicine, Nashville, Tennessee, USA 2Medical Director, Eli Lilly and Company, Indianapolis, Indiana, USA 3Clinical Research Physician, Eli Lilly and Company, Indianapolis, Indiana, USA 4Clinical Research Associate, Eli Lilly and Company, Indianapolis, Indiana, USA 5Head, Department of Intensive Care, Erasme University Hospital, Brussels, Belgium Correspondence: Gordon Bernard, gordon.bernard@ Received: 31 October 2002 Critical Care 2003, 7:155-163 (DOI 10.1186/cc2167) Revisions requested: 16 December 2002 This article is online at /content/7/2/155 © 2003 Bernard et al., licensee BioMed Central Ltd Revisions received: 8 February 2003 (Print ISSN 1364-8535; Online ISSN 1466-609X). This is an Open Accepted: 20 February 2003 Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is Published: 28 February 2003