teratogenic effects of diatom metabolites on sea urchin paracentrotus lividus embryos产生畸形的硅藻代谢物对海胆paracentrotus lividus胚胎.pdfVIP

下载本文档

4
0
约5.71万字
约 18页
2017-09-12 发布于上海
举报
版权申诉

teratogenic effects of diatom metabolites on sea urchin paracentrotus lividus embryos产生畸形的硅藻代谢物对海胆paracentrotus lividus胚胎.pdf

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

teratogenic effects of diatom metabolites on sea urchin paracentrotus lividus embryos产生畸形的硅藻代谢物对海胆paracentrotus lividus胚胎

Mar. Drugs 2010, 8, 950-967; doi:10.3390/md8040950 OPEN ACCESS Marine Drugs ISSN 1660-3397 /journal/marinedrugs Article Teratogenic Effects of Diatom Metabolites on Sea Urchin Paracentrotus lividus Embryos Giovanna Romano *, Antonio Miralto and Adrianna Ianora Stazione Zoologica Anton Dohrn, Villa Comunale 80121 Napoli, Italy; E-Mails: antonio.miralto@szn.it (A.M.); adrianna.ianora@szn.it (A.I.) * Author to whom correspondence should be addressed; E-Mail: giovanna.romano@szn.it; Tel.: +39 081 5833430; Fax: +39 081 7641355. Received: 24 February 2010; in revised form: 6 March 2010 / Accepted: 24 March 2010 / Published: 30 March 2010 Abstract: The diatom-derived polyunsaturated aldehydes (PUAs), 2-trans,4-trans- decadienal, 2-trans,4-trans-octadienal, 2-trans,4-trans,7-octatrienal, 2-trans,4-trans- heptadienal, as well as tridecanal were tested on early and later larval development in the sea urchin Paracentrotus lividus . We also tested the effect of some of the more abundant diatom polyunsaturated fatty acids (PUFAs) on development, in particular 5,8,11,14,17- eicosapentaenoic acid (EPA), one of the main precursors of diatom PUAs, as well as 4,7,10,13,16,19-docosahexaenoic acid (DHA), 6,9,12,15-octadecatetraenoic acid (stearidonic acid), 6,9,12-octadecatrienoic acid (γ-linolenic acid) and 9,12-octadecadienoic acid (linoleic acid). PUAs blocked sea urchin cell cleavage in a dose dependent manner and with increasing chai