药学文档（Pharmaceutical documentation）.docVIP

药学文档（Pharmaceutical documentation） School of pharmacy; Guiyang Medical University Syllabus of medicinal chemistry (for four year pharmacy profession) I. Introduction Medicinal chemistry is the basic course of pharmacy specialty. Medicinal chemistry is the study of chemical medicine with modern scientific methods of chemical structure, physicochemical properties and preparation principle of chemical mechanism and metabolism and structure-activity relationship of drug action, and find ways and methods of the new subject, through the course of teaching, to enable students to master the basic content, effective to provide a theoretical basis for the rational use of existing chemicals, laying the foundation for new drug research. Two. Purpose requirements Students should follow the following requirements after studying this course: 1. master the name of the drug, including English name, structural formula, and familiar with the chemical name. 2. master the classification of drugs, the physical and chemical properties of drugs, and influence the efficacy, toxicity, quality of drugs, or help to study the best formulation of drugs and the main characteristics of drug analysis methods. 3. be familiar with the principles and methods of chemical preparation and structural modification of drugs, and understand the possible impurities in the preparation process to ensure the quality of drugs. Understanding of new drugs, ideas, methods, turning point and the latest development of new drugs. 4.. Using the basic knowledge of biology, molecular pharmacology, enzymology and receptor theory, we should be familiar with the mechanism of action of various kinds of drugs - efficacy, side effects and clinical indications. 5. be familiar with the relationship between chemical structure and biological activity, understand the quantitative structure-activity relationship and the basic approach to find new drugs. 6., by understanding the metabolism of drugs in vivo, we can understand the effic