原创力文档the origin and early evolution of eukaryotes in the light of phylogenomics真核生物的起源和早期演化phylogenomics的光.pdfVIP
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the origin and early evolution of eukaryotes in the light of phylogenomics真核生物的起源和早期演化phylogenomics的光
Koonin Genome Biology 2010, 11:209
/2010/11/5/209
R E V I E W
The origin and early evolution of eukaryotes in the
light of phylogenomics
Eugene V Koonin*
mitochondria (see below). Plants and many unicellular
Abstract
eukaryotes also have another type of organelle, plastids.
Phylogenomics of eukaryote supergroups suggest a h e organizational complexity of the eukaryotic cells is
highly complex last common ancestor of eukaryotes complemented by extremely sophisticated, cross-talking
and a key role of mitochondrial endosymbiosis in the signaling networks [14]. h e main signaling systems in
origin of eukaryotes. eukaryotes are the kinase-phosphatase machinery that
regulates protein function through phosphorylation and
dephosphorylation [15-18]; the ubiquitin network that
governs protein turnover and localization through
Eukaryotes reversible protein ubiquitylation [19-21]; regulation of
h e origin of eukaryotes is a huge enigma and a major translation by microRNAs [22-24]; and regulation of
challenge for evolutionary biology [1-3]. h ere is a sharp transcription at the levels of individual genes and
divide in the organizational complexity of the cell chromatin remodeling [24-27]. E
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