益肾更宁合剂对围绝经期大鼠血清性激素及NO、NOS水平影响实验的研究.pdf

益肾更宁合剂对围绝经期大鼠血清性激素及NO、NOS水平影响的实验研究 ABSTRACT ofthisresearchisto themedicineeffectandmechanismof Objective：Thepurpose study theChinesetraditionalmedicine mixturein YiShenGengNingcuring as human animalwhichhasthesimilar the syndrome．Thetarget pathologicalchanges in the is used radio perimenopausalsyndrome experiment．The immunohistochemicalmethodandelectronic areusedinthisresearch． microscopic SDfemale which加areatthe of15-18monthsandtheother8 Methods：48rats，in age arefrom4tO6 usedinthe 15-18monthsratsare months，are forty randomly experiment．The dividedinto5 modelblank groups：perimenopausalgroup、nilestriol mixturedose mixturemediandose and high group，YiShenGengNinggroup mixturelowdose other 4-6monthratsareinthereference level group．Theeight group．The the oxide of serum estradiol(助)，follicle—stimulating nitricoxide betweensthe radio byusing (N0)and synthase(NOS)arecompared groups indexofthe fromdifferentisalsomeasuredand immunoassay．Besides，theovary groups isobserved． histomorphology Results：The andmediandose YiShenGengNingmixture(high groups)can increasest