妇科患者生殖道感染病原菌分布及耐药性分析.docVIP

妇科患者生殖道感染病原菌分布及耐药性分析 　【摘要】 目的：了解妇科患者生殖道感染病原菌分布及耐药性情况。方法：标本分离培养后，予以鉴定到种并进行相应的药敏试验。结果：5259份生殖道标本分离出3083份阳性标本，培养阳性率为58.6%。这3083株病原菌中，革兰氏阳性菌占检出菌的74.5%，以葡萄球菌和白色念珠菌占多数。革兰氏阴性菌占检出菌的25.5%，以大肠埃希氏菌为主。生殖道感染最常见的病原菌依次为大肠埃希氏菌（占21.7%）,表皮葡萄球菌(占18.4%),真菌(占18.0%,以白色念珠菌为主,占检出真菌的72.9%)腐生葡萄球菌(占11.5%),肠球菌(占10.3%),金黄色葡萄球菌(占9.5%)。大肠埃希氏菌对丁胺卡那，三四代头孢类抗菌素耐药率在15%以下，对氨曲南耐药率在25%以下，而对阿莫西林耐药率在80%以上，对庆大，环丙沙星，复方新诺明，一二代头孢类抗菌素耐药率均在30%以上；葡萄球菌对万古霉素耐药率在2%以下，对三四代头孢类抗菌素耐药率在10%以下，对一二代头孢类抗菌素耐药率在20%左右，对青霉素类，红霉素，环丙沙星，复方新诺明耐药率均在50%以上，对庆大耐药率在80%左右。肠球菌除对万古霉素耐药率在5%以下外，对其余各种抗菌素均有不同程度较高的耐药率。真菌感染率明显上升。结论：临床医生要根据生殖道标本培养结果，合理使用抗菌素，以减少细菌耐药性的产生。 【关键词】 生殖道感染; 病原菌分布; 耐药性 　　Research on the Distribution and Antibiotic Resistance of Bacteria in genital Tract of Gynecology 　　Abatract: Objective: To study the distribution and antibiotic resistance of pathogenic bacteria. Method: The antibiotic susceptibility test were detected after cultring the samples. Result: 3083 of 5259 samples in genital tract were positive specimens(58.6%). Most of the bacteria is staphylococus and candida albicans in the detected gram-positive bacteria(74.5%). while, Colon bacillus is the main gram-negative one(25.5%). And most of the pathogenic bacteria in genital tract is colon bacillus(21.7%) staphylococus epidermidis(18.4%), eumycetes(18.0%), candida is the main bacteria in eumycetes(72.9%). Staphylococus saprophyticus(11.5%), entercocolli (10.3%) and staphylococcus aureus (9.5%). The resistance rate of colon bacillus to amikacin, the third and forth generation cephalosporin, aztreonam, ainoxicillin is lt;15%. lt;25% and 80%, respectively. However which is over 30% to gentamicin, ciprofoxacin and SMZ-TMP. While the resistance rate of staphy lococcus to vancomycin ,the third and forth generation cephalosporin, peniciuin, etc, gentamicin is lt;2%, lt;10%, 20% or so, gt;50%, gt;80% respectively. Eumycetes infection is increased. Conclusion: It’s suggest that the doctor should use the antibiotic according to the cultived result of genital tract to decrea