超声心动图声学定量技术对高血压患者左室功能评价.docVIP

超声心动图声学定量技术对高血压患者左室功能评价 　【摘要】; 目的 应用超声心动图声学定量（AQ）技术评价高血压患者的左室收缩和舒张功能。方法 62例高血压患者和30例正常对照组进行AQ检测，根据左室心肌重量指数（LVMI），高血压又分为高血压LVMI正常组与左室肥厚组。结果 与对照组左室舒张功能指标比较，高血压患者左室充盈异常，舒张早期充盈减低，舒张晚期充盈增强；与高血压LVMI正常组比较，高血压左室肥厚组左室充盈尤其是舒张早期充盈低于高血压LVMI正常组；与对照组左室收缩功能指标比较，高血压LVMI正常组左室收缩功能正常，且处于高血流动力学状态，而高血压左室肥厚组左室收缩功能减低，且低于LVMI正常组；与对照组左室容量指标比较，高血压LVMI正常组左室容量负荷增大，而高血压左室肥厚组差异无显著性。结论 AQ技术为定量评价高血压患者的左室收缩和舒张功能提供了新的方法。 　　 【关键词】; 超声心动图　声学定量　高血压　心功能　左室 　　Abstract:Objective To evaluate left ventricular systolic and diastolic functions in patients with hypertension by acoustic quantification（AQ）technique. Methods Sixtytwo patients with hypertension and 30 control volunteers were studied with AQ technique. The hypertension group was divided into thirty subgroups by left ventricular mass index（LVMI）：normal LVMI subgroup and left ventricular hypertrophy subgroup. Results Compared with indices of left ventricular diastolic function in the control volunteers,patients in normal LVMI subgroup and left ventricular hypertrophy subgroup had significantly impaired left ventricular diastolic function,particullarly in patients in the left ventricular hypertrophy subgroup. Compared with parameters of left ventricular systolic function in control volunteers， patients in normal LVMI snbgroup had increased hemodynamics and normal left ventricular systolic function，however，in left evntricular hypertrophy subgroup，patients had normal hemodynamice and decreased left ventricular systolic function. Compared with volumetric indices of control volunteers，patients in normal LVMI subgroup had significantly increased left ventricular volume，but there was no difference between control group and left ventricular hypertrophy subgroup. Conclusion AQ technique may be used as a method to quantify left ventricular systolic and diastolic function in patients with hypertension. 　　Key words：echocardiogram；acoustic quantification technique；hypertension；; ventricular function；left ventricle 　　高血压病常伴有左室功能异常，严重者可发生心力衰竭，及早明确左室功能情况对治疗预后有重要意义