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干细胞在口腔医学中的研究与应用特点(Research and application of stem cells in stomatology)
干细胞在口腔医学中的研究与应用特点(Research and application of stem cells in stomatology)
Research and application of stem cells in stomatology
Abstract background: dental pulp stem cells, bone marrow stromal stem cells and periodontal ligament stem cells belong to adult stem cells in oral cavity, which have two characteristics of adult stem cells: strong self-renewal ability and differentiation potential. Through further study of various stem cells in the oral cavity, it will help us to further reveal the formation process and mechanism of tooth hard tissue, and then guide the clinical treatment and prevention. Objective: To summarize the characteristics and clinical application of various oral adult stem cells. Results and conclusion: with the in-depth study, adult stem cells in oral cavity will gradually be found, in order to establish a complete database of stem cells, which can provide cell source for tissue engineering study in the oral cavity.
Keywords: stem cells; dental pulp stem cells; bone marrow stromal stem cells; periodontal ligament stem cells; oral medicine; review literature
0 Introduction
Stem cells can be divided into 4 types of [1] according to their origins: adult stem cells: pluripotent stem cells in the fetus, children and adult tissues collectively referred to as adult stem cells. Adult stem cells are those tissue or organ specific stem cells that are used primarily to maintain cell function homeostasis. The embryonic stem cells: refers to before implantation from the inner cell mass of blastocysts in embryonic stem cells, embryonic stem cells have the ability of multi-directional differentiation, self replication, but this study will lead to ethical issues. The fetal stem cells of fetal organ formation in pregnancy: about 3 months, 6 months of pregnancy when fetal organ increases gradually and independent exercise of the placenta, fetal growth is rapid, so all tissues including brain contain stem cells, also for the study of fetal stem cells also have a stro
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