氟比洛芬酯与氯诺昔康对局麻膝关节镜术超前镇痛的效果比较.pdfVIP

氟比洛芬酯与氯诺昔康对局麻膝关节镜术超前镇痛的效果比较 ＊ 魏 民 ，王志刚，刘玉杰，朱娟丽，刘 洋（解放军总医院骨科，北京 100853） + 中图分类号 R971.2；R969.4 文献标志码 A 文章编号 1001-0408（2013）02-0155-03 DOI 10.6039/j.issn.1001-0408.2013.02.23 摘 要 目的：比较氟比洛芬酯与氯诺昔康对局麻膝关节镜术超前镇痛的效果。方法：膝关节骨性关节炎患者90例随机分为3 组，各30例，患者进入手术室后，采用不同方案予以超前镇痛（A 组患者静脉滴入氟比洛芬酯50mg ，B 组患者静脉滴入氯诺昔康8 mg ，C 组患者静脉滴入生理盐水10ml 作为对照）。分别于局麻膝关节镜术中和术后观察疼痛视觉模拟评分（VAS ）。结果：清理髌 上囊滑膜和软骨成形时，A 、B 组患者的VAS 评分均低于C 组，差异有统计学意义（P ＜0.05），而A 组和B 组患者之间的差异无统计 学意义（P ＞0.05）；半月板成形时3组患者之间的差异无统计学意义（P ＞0.05）。术后1h 屈膝90°VAS 评分A 组＜B 组＜C 组，但差 异无统计学意义（P ＞0.05）；术后4h 屈膝90°VAS 评分A 组＜B 组＜C 组，差异有统计学意义（P ＜0.05）。结论：在局麻膝关节镜清 理手术的超前镇痛中，氟比洛芬酯和氯诺昔康均能达到满意的术中镇痛效果，但氟比洛芬酯术后镇痛效果更为显著。 关键词 超前镇痛；氟比洛芬酯；氯诺昔康；局麻；膝关节镜术 Comparison of Preemptive Analgesic Effects of Flurbiprofen Axetil and Lornoxicam during the Knee Ar- throscopy under Local Anesthesia WEI Min ，WANG Zhi-gang ，LIU Yu-jie ，ZHU Juan-li ，LIU Yang （Dept. of Orthpaedics ，General Hospital of PLA ，Beijing 100853，China ） ABSTRACT OBJECTIVE ：To observe the preemptive analgesic effect of flurbiprofen axetil and lornoxicam during the knee ar- throscopy under local anesthesia. METHODS ：90 patients with osteoarthritis of knee were randomly divided into 3 groups with 30 cases in each group. They were given different preemptive analgesic programs ，such as group A received intravenous dripping of flurbiprofen axetil 50mg ，group B received intravenous dripping of lornoxicam 8mg and group C received intravenous dripping of normal saline 10ml as control. Analgesia efficacy was assessed by VAS before and after surgery. RESULTS ：VAS scoring of group A and B during arthroscopic debridement and chondroplasty was significantly lower than that of group C ，there was statistical signif- icance among those groups （P ＜0.05）and there was no significant difference between group A and B （P ＞0.05）. There was no sta- tistical sign